Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693923 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4EPOLBGAASLC16A3 | |
| SCHEMBL10693917 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EPOLBGAASLC16A3 | |
| SCHEMBL265593 | 0.67 | KDM4E (0.72) | ALDH1A1KDM4EPOLBGAASLC16A3 | |
| SCHEMBL3691710 | 0.64 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL266168 | 0.64 | ALDH1A1 (0.66) | ALDH1A1KDM4EPOLBGAASLC16A3 | |
| SCHEMBL10689103 | 0.64 | MEN1 (0.39) | ALDH1A1KDM4EGAASLC16A3SLC16A1 | |
| SCHEMBL27965943 | 0.64 | CA1 (0.50) | ALDH1A1POLBGAANR3C2MEN1 | |
| SCHEMBL9186100 | 0.63 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBGAASLC16A3 | |
| Hydrochloric Acid SCHEMBL15209621 | 0.63 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL18138756 | 0.63 | TUBB1 (0.51) | ALDH1A1KDM4EPOLBSLC16A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |