Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692867 | 0.83 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL10693917 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL7780452 | 0.65 | GAA (0.46) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL10689103 | 0.65 | MEN1 (0.39) | KDM4EALDH1A1GAASLC16A3SLC16A1 | |
| SCHEMBL10788821 | 0.65 | KCNN4 (0.43) | KDM4EALDH1A1POLBSLC16A3NR1H2 | |
| SCHEMBL3691710 | 0.64 | ALDH1A1 (0.55) | KDM4EALDH1A1POLBGAAIDO1 | |
| SCHEMBL265593 | 0.64 | KDM4E (0.72) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL4665615 | 0.64 | ALDH1A1 (0.58) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL9186100 | 0.64 | ALDH1A1 (0.52) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL13133332 | 0.64 | KDM4E (0.61) | KDM4EALDH1A1POLBGAASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |