Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780452 | 0.77 | GAA (0.46) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL10689340 | 0.77 | TP53 (0.42) | KDM4EALDH1A1GAAMAPTCYP3A4 | |
| SCHEMBL10692867 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL10691903 | 0.74 | MEN1 (0.47) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL7780465 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL10693923 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL7781204 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL7773670 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL7778519 | 0.70 | CNR2 (0.43) | KDM4EALDH1A1POLBGAASLC16A3 | |
| SCHEMBL265593 | 0.70 | KDM4E (0.72) | KDM4EALDH1A1POLBGAASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |