Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691231 | 0.79 | HPGD (0.36) | — | |
| SCHEMBL10446753 | 0.79 | NOS3 (0.32) | — | |
| SCHEMBL11007177 | 0.78 | DHFR (0.36) | — | |
| SCHEMBL11306419 | 0.77 | DHFR (0.42) | IMPDH2 | |
| SCHEMBL1573155 | 0.76 | DHFR (0.33) | — | |
| SCHEMBL1572808 | 0.74 | DHFR (0.37) | IMPDH2 | |
| SCHEMBL11839014 | 0.72 | DHFR (0.36) | IMPDH2 | |
| SCHEMBL10714315 | 0.72 | DHFR (0.39) | — | |
| SCHEMBL4245270 | 0.72 | TP53 (0.58) | — | |
| SCHEMBL4716502 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124780-B1 | PROCESS FOR PREPARING 2-ALKYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UBE INDUSTRIES, LTD. (JP) | 1988-03-02 | — | — | EP | claimed |
| US-4539403-A | Process for the preparation of a 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-09-03 | — | — | US | claimed |
| US-4536577-A | Process for preparing 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | claimed |
| EP-0124780-A1 | Process for preparing 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1984-11-14 | — | — | EP | claimed |
| JP-58140079-A | — | — | None | — | — | JP | disclosed |
| JP-59044364-A | — | — | None | — | — | JP | disclosed |
| JP-59048464-A | — | — | None | — | — | JP | disclosed |
| JP-59190975-A | — | — | None | — | — | JP | disclosed |
| US-4794182-A | 2-Alkyl-4-amino-5-aminomethylpyrimidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0124780-B1 | PROCESS FOR PREPARING 2-ALKYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UBE INDUSTRIES, LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |
| US-4539403-A | Process for the preparation of a 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4539403-A | Process for the preparation of a 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4536577-A | Process for preparing 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4536577-A | Process for preparing 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0124780-A1 | Process for preparing 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1984-11-14 | — | — | EP | disclosed |
| EP-0124780-A1 | Process for preparing 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1984-11-14 | — | — | EP | disclosed |
| JP-S59190975-A | PRODUCTION OF 2-ALKYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UBE IND LTD | 1984-10-29 | — | — | JP | disclosed |
| JP-S5948464-A | PREPARATION OF 2-ALKYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UBE IND LTD | 1984-03-19 | — | — | JP | disclosed |
| JP-S5944364-A | PREPARATION OF 2-LAKYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UBE IND LTD | 1984-03-12 | — | — | JP | disclosed |
| JP-S58140079-A | PREPARATION OF 2-ALKYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UBE IND LTD | 1983-08-19 | — | — | JP | disclosed |