SCHEMBL10692912

SCHEMBL10692912

Cc1ccc(S(N)(=O)=O)cc1-c1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.56
CA2 P00918 10/20 0.56
CA12 O43570 8/20 0.56
CA9 Q16790 8/20 0.56
POLB P06746 2/20 0.52
HTT P42858 1/20 0.52
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.44
MMP2 P08253 1/20 0.42
LRRK2 Q5S007 1/20 0.42
CA5A P35218 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27871204 0.79 CA2 (0.64) CA1CA2CA12CA9POLB
SCHEMBL4073850 0.77 CA1 (0.66) CA1CA2CA12CA9POLB
SCHEMBL6669968 0.76 CA2 (0.55) CA1CA2CA12CA9POLB
SCHEMBL28053374 0.75 LRRK2 (0.44) CA1CA2CA12CA9LRRK2
SCHEMBL29363320 0.74 HPGD (0.51) POLBLMNA
SCHEMBL1143026 0.74 ESR2 (0.48) POLBLMNA
SCHEMBL10385111 0.74 HPGD (0.51) POLBLMNA
SCHEMBL6794823 0.74 CA1 (0.66) CA1CA2CA12CA9
SCHEMBL3885125 0.74 CA12 (0.47) CA1CA2CA12CA9POLB
SCHEMBL22381412 0.73 HPGD (0.48) CA2CA12POLBHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 EP disclosed