Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.55 |
| ▸ | CA1 | P00915 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204260 | 0.84 | GAA (0.53) | TSHRCASP1POLBMAPTKDM4E | |
| SCHEMBL563388 | 0.84 | ALDH1A1 (0.55) | TSHRCASP1KDM4EGAAPKM | |
| SCHEMBL5155863 | 0.83 | TSHR (0.45) | TSHRCASP1MAPTKDM4EMEN1 | |
| Water SCHEMBL2538022 | 0.83 | ALDH1A1 (0.53) | TSHRCASP1KDM4EGAAPKM | |
| Hydrochloric Acid SCHEMBL28252264 | 0.83 | ALDH1A1 (0.53) | TSHRCASP1KDM4EGAAPKM | |
| SCHEMBL26936872 | 0.83 | ENPP2 (0.52) | TSHRCASP1GAAPKMLMNA | |
| SCHEMBL13997281 | 0.83 | CA1 (0.61) | CA2CA1CA12CA9CA6 | |
| SCHEMBL29365636 | 0.82 | LMNA (0.61) | CA2CA1CA12CA9CA6 | |
| SCHEMBL233320 | 0.82 | LMNA (0.61) | CA2CA1CA12CA9CA6 | |
| SCHEMBL6282639 | 0.80 | ACHE (0.49) | CA2CA1CA12CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156801-A | A kind of benzo pyran cosmetic and preparation method thereof with antioxidation | 河南湾流生物科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-109879882-A | A kind of benzo pyran cosmetic and preparation method thereof with antioxidation | 河南湾流生物科技有限公司 | 2019-06-14 | — | — | CN | claimed |
| EP-0426243-B1 | Polyamide moulding compositions | T & N TECHNOLOGY LTD (GB) | 1996-03-20 | — | — | EP | claimed |
| CN-110156801-A | A kind of benzo pyran cosmetic and preparation method thereof with antioxidation | 河南湾流生物科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-109879882-A | A kind of benzo pyran cosmetic and preparation method thereof with antioxidation | 河南湾流生物科技有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-108884068-A | 1- cyano-pyrolidin derivative as DUB inhibitor | 特殊治疗有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104053661-B | The thienopyrimidines inhibitor of atypical protein kinase C | 癌症研究技术有限公司 | 2018-06-19 | — | — | CN | disclosed |
| EP-1806620-A1 | MATTE AGENT FOR INFRARED-SENSITIVE PLANOGRAPHIC PRINTING PLATE AND USE THEREOF | Kodak Polychrome Graphics Japan Ltd. (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1118906-B1 | Granulation process using two melting additives | GRABIG TETENAL PHOTOWERK (DE) | 2004-09-22 | — | — | EP | disclosed |
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-1118906-A1 | Granulation process using two melting additives | Tetenal Photowerk GmbH & Co (DE) | 2001-07-25 | — | — | EP | disclosed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | disclosed |
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | disclosed |