Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675633 | 0.82 | CRBN (0.37) | SRD5A1METAP1PARP10PARP11CRBN | |
| SCHEMBL10675643 | 0.82 | CRBN (0.37) | SRD5A1METAP1PARP10PARP11CRBN | |
| SCHEMBL10674343 | 0.82 | SRD5A1 (0.40) | SRD5A1CRBNRAB9AHTR2AHTR2C | |
| SCHEMBL10377619 | 0.82 | NOTUM (0.43) | SRD5A1METAP1CRBNHTR2AHTR2C | |
| SCHEMBL7621632 | 0.78 | CRBN (0.51) | METAP1CRBNRAB9AACHE | |
| SCHEMBL24319166 | 0.77 | CRBN (0.60) | SRD5A1CRBNCSNK1A1HTR2AHTR2C | |
| SCHEMBL26248446 | 0.76 | CRBN (0.46) | SRD5A1CRBNCSNK1A1HTR2AHTR2C | |
| SCHEMBL10690871 | 0.76 | CRBN (0.36) | CRBNAKR1C3AKR1C2 | |
| SCHEMBL10671026 | 0.73 | NOTUM (0.40) | SRD5A1PARP10CRBNHTR2AHTR2C | |
| SCHEMBL10687019 | 0.73 | CRBN (0.40) | SRD5A1METAP1PARP10CRBNAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | disclosed |