Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.50 |
| ▸ | HTR1D | P28221 | 6/20 | 0.50 |
| ▸ | HTR1B | P28222 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HTR5A | P47898 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693037 | 1.00 | HTR1A (0.50) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10692576 | 0.85 | HTR6 (0.56) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10692575 | 0.85 | HTR6 (0.56) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10690033 | 0.84 | HTR6 (0.63) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10690040 | 0.84 | HTR6 (0.63) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10694681 | 0.80 | HTR1D (0.69) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10694676 | 0.80 | HTR1D (0.69) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL10687914 | 0.79 | HTR1A (0.61) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| Oxalic Acid SCHEMBL10693415 | 0.79 | KMT2A (0.53) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| Oxalic Acid SCHEMBL10694021 | 0.79 | HTR1A (0.53) | HTR1AHTR1DHTR1BHTR2AHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785016-A | VASOCONSTRICTION, MIGRAINES ALKANEAMINO, ALKANE SULFONAMIDE INDOLES | GLAXO GROUP LIMITED (GB) | 1988-11-15 | — | — | US | disclosed |