SCHEMBL1069306

SCHEMBL1069306

COc1c[c]cc(C(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16958408 0.81 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TDP1L3MBTL1
SCHEMBL28007784 0.79 ALDH1A1 (0.56) ALDH1A1
SCHEMBL1066949 0.79
SCHEMBL63193 0.77 ALDH1A1 (0.59) ALDH1A1
SCHEMBL3453973 0.77
SCHEMBL1068013 0.76 GPR3 (0.32)
SCHEMBL1067020 0.75 MAPT (0.41) ALDH1A1
SCHEMBL28360321 0.75 ALDH1A1 (0.58) ALDH1A1
SCHEMBL28108949 0.74 ALDH1A1 (0.56) ALDH1A1
SCHEMBL28321856 0.74 ALDH1A1 (0.56) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011006886-A2 AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV BASF SE (DE) 2011-01-20 WO disclosed
WO-2010149758-A1 ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES BASF SE (DE) 2010-12-29 WO disclosed