Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632877 | 0.82 | PNMT (0.59) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL21776127 | 0.78 | PNMT (0.55) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL15302407 | 0.77 | CYP1A2 (0.63) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL423182 | 0.76 | CYP1A2 (0.68) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL22801396 | 0.76 | CYP1A2 (0.68) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL6685393 | 0.76 | PNMT (0.52) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL6684793 | 0.74 | CYP1A2 (0.50) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11501928 | 0.74 | CYP1A2 (0.65) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL6684232 | 0.73 | CYP1A2 (0.49) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL4026098 | 0.73 | PNMT (0.49) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263673-A2 | Addition reaction of hydrosilanes with unsaturated hydrocarbons | Toray Silicone Company, Ltd. (JP) | 1988-04-13 | — | — | EP | disclosed |