SCHEMBL6684232

SCHEMBL6684232

CCCCCCC(C)c1cccc(Cl)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 1/20 0.49
NFKB1 P19838 1/20 0.49
PNMT P11086 1/20 0.49
LMNA P02545 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SOAT1 P35610 1/20 0.37
KDM4E B2RXH2 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684793 0.98 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6NFKB1PNMT
SCHEMBL6685393 0.93 PNMT (0.52) CYP1A2CYP3A4CYP2D6NFKB1PNMT
SCHEMBL6684286 0.86 ADRB2 (0.40) CYP1A2CYP3A4CYP2D6NFKB1LMNA
SCHEMBL21776127 0.86 PNMT (0.55) CYP1A2CYP3A4CYP2D6NFKB1PNMT
SCHEMBL6686875 0.84 ADRB2 (0.41) CYP1A2CYP3A4CYP2D6NFKB1PNMT
SCHEMBL23491328 0.84 SOAT1 (0.38) CYP1A2CYP3A4LMNAMEN1KMT2A
SCHEMBL20178499 0.81 MEN1 (0.43) CYP1A2CYP3A4LMNAALDH1A1MEN1
SCHEMBL29788773 0.80 L3MBTL1 (0.35) ALDH1A1TSHRSOAT1
SCHEMBL24663173 0.80 CYP1A2 (0.44) CYP1A2CYP3A4CYP2D6NFKB1PNMT
SCHEMBL6684349 0.80 CSNK1E (0.42) ALDH1A1MEN1KMT2ATSHRSOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed