Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338349 | 0.90 | RNF4 (0.65) | RNF4MEN1KMT2ATRPM8LTB4R2 | |
| SCHEMBL10693309 | 0.86 | ALOX5 (0.58) | RNF4MEN1KMT2ATRPM8CHRM2 | |
| SCHEMBL5144037 | 0.84 | NPC1 (0.71) | MEN1KMT2ATRPM8LTB4R2NPC1 | |
| SCHEMBL10693518 | 0.83 | RNF4 (0.58) | RNF4MEN1KMT2ATRPM8LTB4R2 | |
| SCHEMBL6783932 | 0.82 | NPC1 (0.70) | RNF4MEN1KMT2ATRPM8LTB4R2 | |
| SCHEMBL18425653 | 0.80 | LTB4R2 (0.77) | LTB4R2 | |
| SCHEMBL10692573 | 0.80 | HTT (0.61) | LTB4R2NPC1RAB9AALDH1A1GLA | |
| SCHEMBL10694289 | 0.80 | ALDH1A1 (0.57) | LTB4R2NPC1RAB9AALDH1A1GLA | |
| SCHEMBL31169773 | 0.80 | RNF4 (0.68) | RNF4MEN1KMT2ATRPM8LTB4R2 | |
| SCHEMBL27493200 | 0.79 | MEN1 (0.57) | RNF4MEN1KMT2ATRPM8CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |