Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 3/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692247 | 0.80 | HPGD (0.43) | KMT2AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL10695779 | 0.75 | ALDH1A1 (0.49) | KMT2AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL10693651 | 0.74 | CTNNB1 (0.36) | IKBKETBK1KMT2AALDH1A1KDM4E | |
| SCHEMBL10693571 | 0.74 | TTR (0.45) | KMT2AALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL10693672 | 0.73 | CTNNB1 (0.35) | IKBKETBK1KMT2AALDH1A1KDM4E | |
| SCHEMBL10691949 | 0.69 | MAPT (0.52) | KMT2AALDH1A1GAAMEN1RAB9A | |
| SCHEMBL10693671 | 0.68 | MAOB (0.53) | KMT2AUSP2MEN1 | |
| SCHEMBL10691933 | 0.64 | KDM4E (0.49) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19708685 | 0.62 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL10692784 | 0.61 | MEN1 (0.33) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |