Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695779 | 0.88 | ALDH1A1 (0.49) | TTRHTTPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10693671 | 0.83 | MAOB (0.53) | MEN1KMT2A | |
| SCHEMBL10692247 | 0.77 | HPGD (0.43) | LMNAL3MBTL1ALDH1A1HPGDNPC1 | |
| SCHEMBL10691712 | 0.75 | SRD5A2 (0.41) | TTRHTTLMNAPOLBSRD5A2 | |
| SCHEMBL10693284 | 0.74 | IKBKE (0.37) | TTRPOLBL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL10693651 | 0.74 | CTNNB1 (0.36) | TTRPOLBALDH1A1HPGDNPC1 | |
| SCHEMBL10693672 | 0.73 | CTNNB1 (0.35) | TTRPOLBALDH1A1HPGDNPC1 | |
| SCHEMBL10691949 | 0.71 | MAPT (0.52) | LMNAPOLBALDH1A1RAB9AMEN1 | |
| SCHEMBL9471701 | 0.70 | TTR (0.57) | TTRHTTLMNAPOLBL3MBTL1 | |
| SCHEMBL11865210 | 0.69 | TTR (0.80) | TTRHTTLMNAALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |