Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.36 |
| ▸ | WNT3A | P56704 | 5/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693672 | 0.89 | CTNNB1 (0.35) | CTNNB1WNT3AIKBKETBK1MEN1 | |
| SCHEMBL10692247 | 0.88 | HPGD (0.43) | CTNNB1WNT3AMEN1KMT2AHPGD | |
| SCHEMBL10695779 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2APOLBMAOBHPGD | |
| SCHEMBL10693284 | 0.74 | IKBKE (0.37) | IKBKETBK1MEN1KMT2APOLB | |
| SCHEMBL10693571 | 0.74 | TTR (0.45) | MEN1KMT2APOLBHPGDTTR | |
| SCHEMBL10691949 | 0.69 | MAPT (0.52) | MEN1KMT2APOLBMAOBALDH1A1 | |
| SCHEMBL9367537 | 0.68 | ALDH1A1 (0.58) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL10693671 | 0.68 | MAOB (0.53) | MEN1KMT2AMAOB | |
| SCHEMBL9368699 | 0.68 | KDM4E (0.68) | POLBKDM4EALDH1A1 | |
| SCHEMBL16806149 | 0.67 | HSD17B3 (0.55) | MEN1KMT2AHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |