Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854458 | 0.82 | ALDH1A1 (0.45) | LMNAALDH1A1HPGDHTTTSHR | |
| SCHEMBL24671951 | 0.77 | HTT (0.60) | CNR1CNR2LMNAALDH1A1HPGD | |
| SCHEMBL10692590 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1HPGDHTTTSHR | |
| SCHEMBL7597614 | 0.72 | CNR1 (0.62) | CNR1CNR2LMNAALDH1A1HPGD | |
| SCHEMBL9472769 | 0.72 | CNR1 (0.54) | CNR1CNR2LMNAALDH1A1HPGD | |
| SCHEMBL10690539 | 0.72 | CNR1 (0.62) | CNR1CNR2LMNAALDH1A1HTT | |
| SCHEMBL30594253 | 0.72 | PDK1 (0.55) | CNR1CNR2LMNAALDH1A1HPGD | |
| Benzylic Acid SCHEMBL27827388 | 0.71 | CYP2C9 (0.53) | LMNAALDH1A1HTTL3MBTL1TSHR | |
| SCHEMBL2845025 | 0.71 | HDAC3 (0.61) | CNR1CNR2LMNAALDH1A1HTT | |
| SCHEMBL9473362 | 0.71 | CNR1 (0.53) | CNR1CNR2LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |