Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694507 | 0.82 | CNR1 (0.40) | ALDH1A1LMNASMN1; SMN2HTTRAB9A | |
| SCHEMBL10691473 | 0.79 | RIPK1 (0.53) | ALDH1A1HPGDLMNASMN1; SMN2GAA | |
| SCHEMBL9501899 | 0.77 | MMP8 (0.50) | ALDH1A1HPGDSMN1; SMN2GAARAB9A | |
| SCHEMBL10693365 | 0.75 | CNR1 (0.54) | ALDH1A1HPGDLMNASMN1; SMN2GAA | |
| SCHEMBL10692779 | 0.75 | POLB (0.61) | HPGDSMN1; SMN2GAARAB9AKDM4E | |
| SCHEMBL10994453 | 0.75 | ACSS2 (0.41) | ALDH1A1HPGDLMNAKDM4ECYP1A2 | |
| SCHEMBL10694465 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1HPGDLMNASMN1; SMN2GAA | |
| SCHEMBL10694310 | 0.74 | HDAC3 (0.43) | ALDH1A1LMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10692252 | 0.74 | MEN1 (0.46) | ALDH1A1HPGDLMNASMN1; SMN2GAA | |
| SCHEMBL10694706 | 0.74 | POLB (0.56) | ALDH1A1HPGDLMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |