Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CDC25B | P30305 | 3/20 | 0.56 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947568 | 0.85 | POLB (0.65) | TSHRALDH1A1HSD17B10CDC25BELANE | |
| SCHEMBL195278 | 0.83 | TSHR (0.75) | TSHRALDH1A1HSD17B10CDC25BLMNA | |
| SCHEMBL29619268 | 0.83 | TSHR (0.75) | TSHRALDH1A1HSD17B10CDC25BLMNA | |
| SCHEMBL133366 | 0.83 | LMNA (0.62) | TSHRALDH1A1CDC25BELANELMNA | |
| SCHEMBL29465556 | 0.83 | LMNA (0.62) | TSHRALDH1A1CDC25BELANELMNA | |
| SCHEMBL9468318 | 0.83 | PBRM1 (0.74) | ALDH1A1HSD17B10CDC25BPBRM1POLB | |
| Methane SCHEMBL15286491 | 0.82 | LMNA (0.61) | TSHRALDH1A1CDC25BELANELMNA | |
| Hydrochloric Acid SCHEMBL642777 | 0.82 | LMNA (0.61) | CDC25BELANELMNANPC1SMN1; SMN2 | |
| SCHEMBL4733499 | 0.81 | PBRM1 (0.48) | ALDH1A1HSD17B10PBRM1ELANEPOLB | |
| SCHEMBL11863445 | 0.80 | LMNA (0.53) | TSHRALDH1A1HSD17B10PBRM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783472-A | 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-11-08 | — | — | US | disclosed |