Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201247 | 0.85 | ALDH1A1 (0.52) | CRHBPCRHR2LMNAPOLBALDH1A1 | |
| SCHEMBL10693398 | 0.81 | TSHR (0.60) | PBRM1LMNAPOLBNPC1MITF | |
| SCHEMBL6231293 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL9468318 | 0.78 | PBRM1 (0.74) | PBRM1LMNAPOLBNPC1MITF | |
| SCHEMBL8546366 | 0.76 | ALDH1A1 (0.60) | LMNAPOLBNPC1ALDH1A1ADRA1A | |
| SCHEMBL2989810 | 0.74 | ALDH1A1 (0.68) | POLBALDH1A1ADRA1AKDM4ESCN1A | |
| SCHEMBL8880799 | 0.74 | ALDH1A1 (0.52) | ALDH1A1ADRA1ASCN1ASCN2ASCN3A | |
| SCHEMBL5375275 | 0.74 | MAPT (0.48) | LMNAPOLBNPC1SCN1ASCN2A | |
| SCHEMBL28815185 | 0.73 | TSHR (0.70) | LMNAALDH1A1ADRA1AKDM4ESCN1A | |
| SCHEMBL11863445 | 0.73 | LMNA (0.53) | PBRM1LMNAPOLBNPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060844-A1 | POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ALBEMARLE CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |