SCHEMBL10693412

SCHEMBL10693412

Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
PGR P06401 3/20 0.59
POLB P06746 1/20 0.59
MAPT P10636 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MEN1 O00255 2/20 0.56
PKM P14618 2/20 0.56
ALDH1A1 P00352 1/20 0.56
KEAP1 Q14145 2/20 0.55
IL1RN P18510 1/20 0.55
ERAP1 Q9NZ08 1/20 0.55
CA9 Q16790 5/20 0.54
CA2 P00918 4/20 0.54
CA12 O43570 4/20 0.54
CA1 P00915 3/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA14 Q9ULX7 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3320242 0.87 MAPT (0.73) KMT2APGRPOLBMAPTNPSR1
SCHEMBL5225275 0.87 CES1 (0.66) PGRMAPTNPSR1PKMALDH1A1
SCHEMBL5737571 0.86 CA1 (0.67) KMT2AMAPTNPSR1MEN1PKM
SCHEMBL7579053 0.85 PGR (0.75) KMT2APGRMAPTMEN1PKM
SCHEMBL10692669 0.84 MAPT (0.57) KMT2APGRMAPTNPSR1ALDH1A1
SCHEMBL11689074 0.83 KMT2A (0.59) KMT2APGRPOLBMAPTMEN1
SCHEMBL5737038 0.81 PGR (0.63) KMT2APGRPOLBMAPTMEN1
SCHEMBL8530932 0.81 KMT2A (0.60) KMT2APGRPOLBMAPTMEN1
SCHEMBL3773473 0.81 PGR (0.64) KMT2APGRMAPTNPSR1MEN1
SCHEMBL11680178 0.80 HTR6 (0.48) KMT2APGRMAPTNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed