Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.48 |
| ▸ | GNG2 | P59768 | 3/20 | 0.46 |
| ▸ | GNB1 | P62873 | 3/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696297 | 0.88 | RAPGEF4 (0.68) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10389482 | 0.87 | ALDH1A1 (0.49) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10693653 | 0.84 | RAPGEF4 (0.59) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10693431 | 0.84 | RAPGEF4 (0.59) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL9153370 | 0.83 | ALDH1A1 (0.80) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10389480 | 0.80 | RAPGEF4 (0.48) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10388839 | 0.80 | RAPGEF4 (0.48) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10388837 | 0.80 | L3MBTL1 (0.50) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL9878671 | 0.80 | ALDH1A1 (0.51) | TDP1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10389136 | 0.77 | RAPGEF4 (0.45) | TDP1ALDH1A1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |