SCHEMBL10693457

SCHEMBL10693457

CC(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)N(C)C

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
LIPE Q05469 14/20 0.56
SCN9A Q15858 1/20 0.56
RAB9A P51151 1/20 0.52
MAPT P10636 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
BCHE P06276 1/20 0.50
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10500247 0.88 LMNA (0.53) LMNALIPESCN9ARAB9AMAPT
SCHEMBL9450015 0.87 LMNA (0.55) LMNALIPESCN9ARAB9AMAPT
Fluazifop SCHEMBL1010239 0.86 LMNA (0.62) LMNALIPERAB9AMAPTNPSR1
Fluazifop SCHEMBL29370478 0.86 LMNA (0.62) LMNALIPERAB9AMAPTNPSR1
Fluazifop-P SCHEMBL118853 0.86 LMNA (0.62) LMNALIPERAB9AMAPTNPSR1
Fluazifop SCHEMBL67403 0.86 LMNA (0.62) LMNALIPERAB9AMAPTNPSR1
Fluazifop SCHEMBL1559717 0.86 LMNA (0.62) LMNALIPERAB9AMAPTNPSR1
Fluazifop-P SCHEMBL29370487 0.86 LMNA (0.62) LMNALIPERAB9AMAPTNPSR1
SCHEMBL10844569 0.86 LIPE (0.57) LMNALIPESCN9ARAB9AMAPT
Fluazifop-P SCHEMBL11006621 0.85 LMNA (0.60) LMNALIPERAB9AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4753673-A GRASSY WEEDS THE DOW CHEMICAL COMPANY (US) 1988-06-28 US disclosed
US-4628099-A INTERMEDIATES FOR HERBICIDES THE DOW CHEMICAL COMPANY (US) 1986-12-09 US disclosed
US-4551170-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-11-05 US disclosed
US-4523017-A REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND THE DOW CHEMICAL COMPANY (US) 1985-06-11 US disclosed
US-4491468-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-01-01 US disclosed
US-4479001-A Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1984-10-23 US disclosed
EP-0000483-B1 TRIFLUOROMETHYL PYRIDINYL(OXY/THIO)PHENOXY PROPANOIC ACIDS AND PROPANOLS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 1981-10-14 EP disclosed