Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517612 | 0.82 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1071167 | 0.81 | SLC6A2 (0.43) | — | |
| SCHEMBL1069090 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL8829551 | 0.79 | — | — | |
| SCHEMBL202404 | 0.72 | ALDH1A1 (0.61) | TTRALBHPGDSALDH1A1CYP2A6 | |
| SCHEMBL2461839 | 0.72 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1 | |
| 4-Cyanophenol SCHEMBL11239056 | 0.71 | CA2 (0.59) | MEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL2814132 | 0.70 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL509576 | 0.70 | ALDH1A1 (0.58) | TTRALBHPGDSALDH1A1CYP2A6 | |
| SCHEMBL18925852 | 0.70 | BACE1 (0.35) | TTRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946355-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2015-02-03 | — | — | US | disclosed |
| EP-2448984-B1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-20120136113-A1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2448984-A2 | HYDROXYARYL FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002930-A2 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | WO | disclosed |