Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Cyanophenol SCHEMBL11239056 | 0.90 | CA2 (0.59) | ALDH1A1CYP2A6CA2CA9CA1 | |
| SCHEMBL4763549 | 0.80 | CA1 (0.39) | ALDH1A1CA2CA9CA1CA12 | |
| SCHEMBL1067888 | 0.79 | PREP (0.43) | ALDH1A1CYP2A6CA2CA9CA1 | |
| SCHEMBL16215337 | 0.79 | KIF11 (0.42) | ALDH1A1CA2CA9CA1HRH3 | |
| SCHEMBL1069352 | 0.79 | TTR (0.38) | ALDH1A1CYP2A6MEN1KMT2A | |
| SCHEMBL30203020 | 0.77 | CA2 (0.46) | ALDH1A1CYP2A6CA2CA9CA1 | |
| SCHEMBL1071167 | 0.75 | SLC6A2 (0.43) | NOTUM | |
| Oxirane SCHEMBL7119447 | 0.74 | MAOA (0.53) | ALDH1A1CYP2A6CA2CA9CA1 | |
| SCHEMBL103904 | 0.73 | MAOB (0.61) | ALDH1A1CYP2A6CA2CA9CA1 | |
| 1,4-Dimethoxybenzene SCHEMBL28617696 | 0.73 | MAOB (0.61) | ALDH1A1CYP2A6CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946355-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2015-02-03 | — | — | US | disclosed |
| EP-2448984-B1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-20120136113-A1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2448984-A2 | HYDROXYARYL FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002930-A2 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | WO | disclosed |