Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26447159 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL4838392 | 0.80 | RAPGEF4 (0.40) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL14975100 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL2633660 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL12326164 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL2955343 | 0.74 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL13067432 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL282134 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL10932995 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 | |
| SCHEMBL6028138 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3086791-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | University of Florida Research Foundation, Inc. (US) | 2016-11-02 | — | — | EP | disclosed |
| EP-2917203-A1 | PYRROL-1 -YL BENZOIC ACID DERIVATIVES USEFUL AS MYC INHIBITORS | Dana-Farber Cancer Institute, Inc. (US) | 2015-09-16 | — | — | EP | disclosed |
| WO-2015100331-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-07-02 | — | — | WO | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2790697-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | University of Florida Research Foundation, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| WO-2014071247-A1 | PYRROL-1 -YL BENZOIC ACID DERIVATES USEFUL AS MYC INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-05-08 | — | — | WO | disclosed |
| WO-2013090750-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| EP-2569019-A2 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2012075456-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2011006088-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010093918-A1 | APOLIPOPROTEIN A-I MIMICS | CERENIS THERAPEUTICS SA (FR) | 2010-08-19 | — | — | WO | disclosed |
| US-20090203672-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| CN-100475825-C | Acyclic nucleoside phosphonate derivatives | INST PHARM & TOXICOLOGY AMMS (CN) | 2009-04-08 | — | — | CN | disclosed |
| WO-2008002849-A2 | ARYL SULFONES | NEUROGEN CORPORATION (US) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008002849-A2 | ARYL SULFONES | NEUROGEN CORPORATION (US) | 2008-01-03 | — | — | WO | disclosed |
| WO-2007140383-A2 | SPIROCYCLIC SULFONAMIDES AND RELATED COMPOUNDS | NEUROGEN CORPORATION (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007140383-A2 | SPIROCYCLIC SULFONAMIDES AND RELATED COMPOUNDS | NEUROGEN CORPORATION (US) | 2007-12-06 | — | — | WO | disclosed |
| EP-1674477-A2 | Binding polypeptides for B lymphocyte stimulator protein (BLYS) | Dyax Corp. (US) | 2006-06-28 | — | — | EP | disclosed |
| CN-1670024-A | Acyclic nucleoside phosphonate derivatives | INST PHARM & TOXICOLOGY AMMS (CN) | 2005-09-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203672-A1 | Substituted Sulfonamide Compounds | RPS4X, RPS4Y1, CACNA1A | ALDH1A1 1731/4885CYP3A4 2714/4885HPGD 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.