Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111705 | 0.85 | RAB9A (0.57) | KCNK3KCNK9RXFP1NPC1RAB9A | |
| SCHEMBL10690439 | 0.82 | NPC1 (0.47) | RXFP1NPC1RAB9AMEN1TP53 | |
| SCHEMBL9501813 | 0.79 | HTT (0.45) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL2662445 | 0.78 | ALPL (0.61) | RXFP1NPC1RAB9APKMTP53 | |
| SCHEMBL9501827 | 0.78 | POLB (0.40) | KCNK3KCNK9RXFP1NPC1RAB9A | |
| SCHEMBL11562864 | 0.77 | KLKB1 (0.53) | KCNK3KCNK9RXFP1NPC1RAB9A | |
| SCHEMBL11110352 | 0.77 | POLB (0.57) | RXFP1NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL11105640 | 0.76 | KDM4E (0.60) | RXFP1NPC1RAB9AMEN1TP53 | |
| SCHEMBL10690551 | 0.76 | ALPL (0.43) | NPC1RAB9ABRPF1SMN1; SMN2CASP3 | |
| SCHEMBL10792558 | 0.76 | KMT2A (0.43) | RXFP1NPC1RAB9APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764525-A | N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-16 | — | — | US | disclosed |