Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL27387677 | 0.86 | TP53 (0.65) | RAB9AALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL10900520 | 0.86 | MAPT (0.61) | RAB9ANPC1HPGDALDH1A1BAZ1A | |
| SCHEMBL3234327 | 0.84 | CES2 (0.68) | ALDH1A1MAPTTDP1CES2CES1 | |
| SCHEMBL6326580 | 0.84 | ALDH1A1 (0.68) | RAB9ANPC1HPGDALDH1A1MAPT | |
| SCHEMBL181572 | 0.84 | CES2 (0.78) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL961431 | 0.83 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1MAPTTDP1 | |
| SCHEMBL8962651 | 0.83 | CES2 (0.66) | ALDH1A1MAPTTDP1CES2CES1 | |
| SCHEMBL8962645 | 0.83 | CES2 (0.66) | ALDH1A1MAPTTDP1CES2CES1 | |
| Methyl Alcohol SCHEMBL27717832 | 0.83 | TP53 (0.69) | RAB9AALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL333455 | 0.82 | TP53 (0.73) | ALDH1A1MAPTTDP1SMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783472-A | 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-11-08 | — | — | US | disclosed |