Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900520 | 0.88 | MAPT (0.61) | ALDH1A1MAPTHPGDSRD5A2MAPK1 | |
| SCHEMBL218018 | 0.87 | MAPT (0.78) | ALDH1A1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31155755 | 0.85 | ATM (0.57) | ALDH1A1MAPTMAPK1TDP1L3MBTL1 | |
| Hydrogen Sulfide SCHEMBL28326954 | 0.85 | MAPT (0.75) | ALDH1A1MAPTMAPK1TDP1L3MBTL1 | |
| Phosphine SCHEMBL30201038 | 0.85 | MAPT (0.75) | ALDH1A1MAPTMAPK1TDP1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL29558993 | 0.85 | MAPT (0.75) | ALDH1A1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10723714 | 0.84 | SRD5A2 (0.83) | ALDH1A1MAPTSRD5A2MAPK1TDP1 | |
| SCHEMBL975118 | 0.84 | SRD5A2 (0.83) | ALDH1A1MAPTSRD5A2MAPK1TDP1 | |
| SCHEMBL10693570 | 0.84 | RAB9A (0.58) | ALDH1A1MAPTHPGDTDP1TSHR | |
| SCHEMBL11750739 | 0.84 | MAPT (0.60) | ALDH1A1MAPTHPGDMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 155/4885MAPT 3022/4885HPGD 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.