Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.61 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18210636 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL17962981 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL10693602 | 0.91 | ALDH1A1 (0.64) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL30986129 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL17065552 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL825278 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL5520736 | 0.83 | LMNA (0.62) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL17165009 | 0.82 | LMNA (0.54) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL10701463 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 | |
| SCHEMBL3867322 | 0.81 | ALDH1A1 (0.65) | SMN1; SMN2PLA2G1BPLA2G2ANR5A2NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022289-A1 | NOVEL PHOSPHOLIPASE A2 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022289-A1 | NOVEL PHOSPHOLIPASE A2 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-23 | — | — | WO | disclosed |