Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111407 | 0.86 | STAT3 (0.52) | ADRB2ALDH1A1LMNANPSR1SLC22A1 | |
| SCHEMBL10695551 | 0.84 | PDE4A (0.48) | ADRB2ALDH1A1LMNACYP3A4STAT3 | |
| Hydrochloric Acid SCHEMBL10695075 | 0.83 | PDE4A (0.48) | ADRB2ALDH1A1LMNACYP3A4STAT3 | |
| SCHEMBL27673600 | 0.78 | STAT3 (0.71) | ADRB2CYP3A4STAT3KDM4EATM | |
| SCHEMBL8717228 | 0.78 | ALOX15 (0.56) | ADRB2ALDH1A1LMNANPSR1SLC22A1 | |
| SCHEMBL8717235 | 0.78 | ALOX15 (0.56) | ADRB2ALDH1A1LMNANPSR1SLC22A1 | |
| SCHEMBL25287578 | 0.75 | STAT3 (0.61) | ADRB2ALDH1A1LMNANPSR1SLC22A1 | |
| SCHEMBL25287579 | 0.75 | STAT3 (0.61) | ADRB2ALDH1A1LMNANPSR1SLC22A1 | |
| SCHEMBL3578334 | 0.75 | STAT3 (0.87) | ADRB2CYP3A4STAT3KDM4EATM | |
| SCHEMBL3592223 | 0.74 | ALDH1A1 (0.51) | ADRB2ALDH1A1LMNANPSR1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253592-A1 | A method for epimerizing an optically active benzylalcohol derivative | TANABE SEIYAKU CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0107149-A1 | Novel naphthalene derivatives and method for preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1984-05-02 | — | — | EP | disclosed |
| EP-0106335-A2 | Pharmaceutical composition and a method for enhancing the absorption of a pharmaceutically active compound | Tanabe Seiyaku Co., Ltd. (JP) | 1984-04-25 | — | — | EP | disclosed |