Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751022 | 0.79 | STAT3 (0.55) | ALDH1A1ADRB2CYP3A4STAT3PPARG | |
| SCHEMBL16953953 | 0.75 | PPARG (0.62) | ALDH1A1LMNANPSR1CYP3A4TSHR | |
| SCHEMBL9836311 | 0.74 | PPARG (0.51) | ALDH1A1LMNANPSR1PPARGPPARD | |
| SCHEMBL10693648 | 0.74 | ADRB2 (0.57) | ALDH1A1LMNANPSR1SLC22A1ADRB2 | |
| SCHEMBL11617314 | 0.72 | MEN1 (0.40) | ALDH1A1ADRB2MEN1KMT2ACA2 | |
| SCHEMBL7465208 | 0.72 | PPARG (0.43) | LMNAPPARGPPARDPPARA | |
| SCHEMBL16960024 | 0.72 | PPARG (0.49) | ALDH1A1LMNANPSR1PPARGPPARD | |
| SCHEMBL13078133 | 0.71 | STAT3 (0.52) | ALDH1A1LMNANPSR1SLC22A1ADRB2 | |
| SCHEMBL22192868 | 0.71 | LMNA (0.67) | ALDH1A1LMNANPSR1SLC22A1ADRB2 | |
| SCHEMBL27817906 | 0.70 | STAT3 (0.63) | ALDH1A1CYP3A4STAT3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858631-B2 | Substituted pyrido [2,3-d] pyrimidinone compounds | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20060235019-A1 | Substituted quinazolinone compounds | CHIRON CORPORATION | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235019-A1 | Substituted quinazolinone compounds | MC4R, MC2R, MC5R | ALDH1A1 2699/4885LMNA 3389/4885NPSR1 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.