SCHEMBL10693669

SCHEMBL10693669

O=S(=O)(Cl)c1ccc(F)c2nonc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
CHRM1 P11229 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
NR1H2 P55055 1/20 0.35
TP53 P04637 2/20 0.34
TET2 Q6N021 2/20 0.33
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TRPV4 Q9HBA0 2/20 0.33
NLRP3 Q96P20 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2530974 0.83 POLB (0.40) POLBKMT2ACHRM1RORARORC
SCHEMBL571688 0.81 TET2 (0.46) POLBKMT2ACHRM1RORARORC
Ammonia Solution, Strong SCHEMBL591415 0.80 TET2 (0.45) POLBKMT2ACHRM1RORARORC
SCHEMBL985487 0.79 RORA (0.47) POLBKMT2ARORARORCNR1H2
SCHEMBL3501293 0.78 RORA (0.35) KMT2ARORARORCNR1H2TP53
SCHEMBL4309721 0.78 RORA (0.46) POLBKMT2ARORARORCNR1H2
SCHEMBL19143549 0.78 POLB (0.36) POLBKMT2ARORARORCNR1H2
SCHEMBL1893522 0.77 HDAC4 (0.45) POLBKMT2ACHRM1ALDH1A1EPAS1
SCHEMBL14008404 0.77 POLB (0.35) POLBKMT2ACHRM1RORARORC
SCHEMBL16049817 0.74 SMN1; SMN2 (0.34) POLBKMT2ATET2ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119876107-A Alkali-resistant staphylococcus aureus phage recombinant lyase, preparation method and application thereof 上海交通大学 2025-04-25 CN claimed
CN-115851689-A Chimeric lyase PlySs2E-V12C and application thereof, recombinant plasmid and recombinant strain 中南民族大学 2023-03-28 CN claimed
CN-114195731-A Hydrogenated nitrosyl donor compound and preparation method thereof 海南大学 2022-03-18 CN claimed
CN-119876107-A Alkali-resistant staphylococcus aureus phage recombinant lyase, preparation method and application thereof 上海交通大学 2025-04-25 CN disclosed
CN-117166275-A Method for improving drainage of wheat straw chemi-mechanical pulp and increasing paper drying rate 南京林业大学 2023-12-05 CN disclosed
CN-111812066-B Biosensor based on CRISPR/Cas12a system, kit and application thereof in small molecule detection 华东理工大学 2023-04-28 CN disclosed
CN-113943545-B Adhesive, composition, aqueous dispersion, dipping solution for dipping and application thereof 马鞍山科英合成材料有限公司 2023-04-25 CN disclosed
CN-115851689-A Chimeric lyase PlySs2E-V12C and application thereof, recombinant plasmid and recombinant strain 中南民族大学 2023-03-28 CN disclosed
CN-114195731-A Hydrogenated nitrosyl donor compound and preparation method thereof 海南大学 2022-03-18 CN disclosed
US-4769467-A Fluorogenic 2,1,3-benzoxadiazoles and fluorometric amine/thiol assays therewith OREAD LABORATORIES, INC. (US) 1988-09-06 US disclosed