Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 13/20 | 0.38 |
| ▸ | THRB | P10828 | 12/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693647 | 0.89 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL8785344 | 0.88 | ALDH1A1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL10692241 | 0.86 | HPGD (0.48) | ALDH1A1 | |
| SCHEMBL9670891 | 0.72 | GSR (0.58) | THRATHRBGSR | |
| Iodomethane SCHEMBL9706765 | 0.71 | GSR (0.40) | THRATHRBSLC6A4GSR | |
| SCHEMBL10538218 | 0.68 | EGFR (0.48) | THRATHRBSLC6A4KDM4EGSR | |
| SCHEMBL10691942 | 0.68 | XDH (0.49) | ALDH1A1 | |
| SCHEMBL13488541 | 0.68 | ALDH1A1 (0.64) | KDM4EALDH1A1 | |
| SCHEMBL10693893 | 0.67 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL11780746 | 0.66 | NPC1 (0.53) | THRATHRBSLC6A4SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |