Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 13/20 | 0.39 |
| ▸ | THRB | P10828 | 11/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348992 | 0.82 | ATM (0.50) | HPGD | |
| Iodomethane SCHEMBL9590125 | 0.80 | EGFR (0.35) | EGFRHPGD | |
| SCHEMBL9437729 | 0.79 | PTPN1 (0.40) | HPGD | |
| SCHEMBL7349547 | 0.77 | MAPT (0.49) | HPGD | |
| SCHEMBL9590401 | 0.77 | EGFR (0.36) | EGFRHPGD | |
| SCHEMBL10691664 | 0.71 | ALDH1A1 (0.50) | HPGD | |
| SCHEMBL10693708 | 0.71 | THRA (0.38) | GSRTHRATHRBSLC6A4 | |
| SCHEMBL7343586 | 0.71 | TDP2 (0.34) | — | |
| SCHEMBL15969068 | 0.71 | CTNNB1 (0.64) | HPGD | |
| SCHEMBL10027732 | 0.71 | HPGD (0.70) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011256-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZINYLTETRAHYDROPYRIDAZINES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-07-09 | — | — | WO | disclosed |