SCHEMBL10693909

SCHEMBL10693909

c1ccc(CCCNOCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.57
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
BCHE P06276 2/20 0.50
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
HPGD P15428 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1829762 0.88 NPC1 (0.50) SIGMAR1BCHEL3MBTL1
SCHEMBL437919 0.88 MAOA (0.48) SIGMAR1L3MBTL1
Hydrochloric Acid SCHEMBL6436425 0.86 GAA (0.50) SIGMAR1MEN1KMT2ABCHEL3MBTL1
SCHEMBL8724007 0.82 HRAS (0.47) MEN1KMT2APOLB
SCHEMBL10106345 0.82 FDFT1 (0.52) BCHE
Hydrochloric Acid SCHEMBL7870266 0.81 SIGMAR1 (0.44) SIGMAR1MEN1KMT2AL3MBTL1HPGD
SCHEMBL27753131 0.81 SIGMAR1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1HPGD
SCHEMBL9781675 0.79 SIGMAR1 (0.51) SIGMAR1MEN1KMT2AHPGD
SCHEMBL12802756 0.79 SIGMAR1 (0.51) SIGMAR1MEN1KMT2AHPGD
SCHEMBL8863637 0.79 MAOA (0.47) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed
US-4792560-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS RORER PHARMACEUTICAL CORPORATION (US) 1988-12-20 US disclosed
EP-0196674-A2 Hydroxamates as modulators of arachidonic acid metabolic pathways USV PHARMACEUTICAL CORPORATION (US) 1986-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 SIGMAR1 163/4885MEN1 235/4885KMT2A 2592/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 SIGMAR1 146/4885MEN1 197/4885KMT2A 2897/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 SIGMAR1 3689/4885MEN1 59/4885KMT2A 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.