Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863637 | 0.91 | MAOA (0.47) | MAOAHRASSIGMAR1CHRM2NPC1 | |
| SCHEMBL9435055 | 0.91 | HRAS (0.41) | MAOAHRASSIGMAR1CHRM2TSHR | |
| SCHEMBL12802756 | 0.91 | SIGMAR1 (0.51) | HRASSIGMAR1 | |
| SCHEMBL9775285 | 0.91 | SIGMAR1 (0.51) | HRASSIGMAR1 | |
| SCHEMBL9781675 | 0.91 | SIGMAR1 (0.51) | HRASSIGMAR1 | |
| SCHEMBL8893077 | 0.91 | SIGMAR1 (0.51) | HRASSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8864207 | 0.89 | MAOA (0.46) | MAOAHRASSIGMAR1CHRM2NPC1 | |
| SCHEMBL10693909 | 0.88 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1 | |
| SCHEMBL3424944 | 0.86 | HTT (0.55) | TSHRNPC1RAB9A | |
| SCHEMBL8724007 | 0.86 | HRAS (0.47) | HRASTSHRNPC1RAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139456-B2 | Chelating compounds and immobilized tethered chelators | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-09-22 | — | — | US | disclosed |
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, TTPA, SLC39A7 | MAOA 1174/4885HRAS 4771/4885SIGMAR1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.