Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693327 | 0.91 | XDH (0.49) | MAOBMAOACXCL12CYP1B1RELA | |
| SCHEMBL10691543 | 0.79 | MAOB (0.53) | MAOBMAOACXCL12ABCG2CYP1B1 | |
| SCHEMBL10693667 | 0.79 | MAOB (0.53) | MAOBMAOACXCL12ABCG2CYP1B1 | |
| SCHEMBL9462343 | 0.77 | MAPT (0.46) | MAOBMAOACYP1B1 | |
| SCHEMBL9462345 | 0.77 | MAPT (0.46) | MAOBMAOACYP1B1 | |
| SCHEMBL10694710 | 0.71 | XDH (0.49) | MAOBMAOACXCL12CYP1B1RELA | |
| SCHEMBL10691942 | 0.71 | XDH (0.49) | MAOBMAOACXCL12ABCG2CYP1B1 | |
| 4',4-Dichlorochalcone SCHEMBL659210 | 0.69 | MAOB (0.86) | MAOBMAOACXCL12ABCG2CYP1B1 | |
| 4',4-Dichlorochalcone SCHEMBL659211 | 0.69 | MAOB (0.86) | MAOBMAOACXCL12ABCG2CYP1B1 | |
| SCHEMBL16052573 | 0.69 | MAOB (0.85) | MAOBMAOACXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |