Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694029 | 0.88 | HTR2A (0.49) | MAOBMAOAHTR2AKDM4EALDH1A1 | |
| SCHEMBL10691148 | 0.87 | MAOA (0.49) | MAOBMAOAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10973045 | 0.86 | MTNR1A (0.37) | CYP1A2HTR1ATDP1 | |
| SCHEMBL10695867 | 0.85 | HASPIN (0.40) | HTR2ACYP1A2HASPINHTR1AHTR1D | |
| SCHEMBL10693816 | 0.79 | HTR1B (0.51) | MAOBMAOACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10693307 | 0.79 | HTR1B (0.50) | MAOBMAOAHTR2AKDM4EALDH1A1 | |
| SCHEMBL10691598 | 0.75 | HPGD (0.50) | HTR1ATDP1 | |
| SCHEMBL10691295 | 0.74 | HTR1B (0.60) | KDM4EALDH1A1CYP1A2CYP2D6TDP1 | |
| SCHEMBL10692799 | 0.74 | HTR1B (0.60) | KDM4EALDH1A1CYP1A2CYP2D6TDP1 | |
| SCHEMBL10691756 | 0.74 | HTR1B (0.60) | KDM4EALDH1A1CYP1A2CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |