Chlorpyrifos

Chlorpyrifos

SCHEMBL1069405

CCOP(=S)(OCC)Oc1nc(Cl)c(Cl)cc1Cl.COP(=S)(OC)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.89
TDP1 Q9NUW8 5/20 0.89
MAPT P10636 4/20 0.89
CYP3A4 P08684 4/20 0.89
TSHR P16473 4/20 0.89
HSD17B10 Q99714 3/20 0.89
MAPK1 P28482 2/20 0.89
ALOX15 P16050 1/20 0.89
ALOX12 P18054 1/20 0.89
ATM Q13315 1/20 0.89
L3MBTL1 Q9Y468 1/20 0.89
MEN1 O00255 2/20 0.80
KMT2A Q03164 2/20 0.80
KDM4E B2RXH2 3/20 0.40
TP53 P04637 1/20 0.38
ACHE P22303 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA3 P07451 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorpyrifos SCHEMBL7908295 0.94 ALDH1A1 (1.00) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL21680 0.94 ALDH1A1 (1.00) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL28566223 0.93 ALDH1A1 (0.97) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL28343022 0.93 ALDH1A1 (0.97) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL14915191 0.93 ALDH1A1 (0.97) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL29011072 0.93 ALDH1A1 (0.97) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL28945660 0.93 ALDH1A1 (0.97) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL18228939 0.93 ALDH1A1 (0.97) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL29037286 0.91 ALDH1A1 (0.94) ALDH1A1TDP1MAPTCYP3A4TSHR
Chlorpyrifos SCHEMBL8502929 0.90 ALDH1A1 (0.91) ALDH1A1TDP1MAPTCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130288990-A1 CONTROLLING PESTS BY COMBINING INSECTICIDES AND TRANSGENIC PLANTS BY APPLYING DIRECTLY TO LEAVES AND ROOTS BAYER CROPSCIENCE AG (DE) 2013-10-31 US claimed
WO-2023189602-A1 PYRIDAZINONE COMPOUND OR SALT THEREOF AND PEST CONTROL AGENT CONTAINING SAME 石原産業株式会社 2023-10-05 WO disclosed
WO-2023176458-A1 DISINFECTING COMPOSITION CONTAINING THIAZOLE CARBOXYLIC ACID HYDRAZIDE COMPOUND 石原産業株式会社 2023-09-21 WO disclosed
WO-2022071428-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME 住友化学株式会社 2022-04-07 WO disclosed
WO-2022004704-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES 住友化学株式会社 2022-01-06 WO disclosed
WO-2020158889-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME 住友化学株式会社 2020-08-06 WO disclosed
EP-2285741-A2 SILICA DISPERSION Evonik Degussa GmbH (DE) 2011-02-23 EP disclosed
EP-2268138-A2 SILICON DIOXIDE DISPERSION Evonik Degussa GmbH (DE) 2011-01-05 EP disclosed
WO-2009095139-A2 SILICA DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 WO disclosed
WO-2009095141-A2 SILICON DIOXIDE DISPERSION EVONIK DEGUSSA GMBH (DE) 2009-08-06 WO disclosed
EP-1765072-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS Akzo Nobel N.V. (NL) 2007-03-28 EP disclosed
WO-2006019772-A1 USE OF PHOSPHATED ALCANOLS AS DISPERSANTS, EMULSIFIERS, HYDROTROPES, WETTING AGENTS AND COMPATABILITY AGENTS IN AGRICULTURAL COMPOSITIONS AKZO NOBEL N.V. (NL) 2006-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130288990-A1 CONTROLLING PESTS BY COMBINING INSECTICIDES AND TRANSGENIC PLANTS BY APPLYING DIRECTLY TO LEAVES AND ROOTS AADAC, ATL3, ANTXR2 ALDH1A1 1444/4885TDP1 4026/4885MAPT 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.