Chlorpyrifos

Chlorpyrifos

SCHEMBL7908295

CCOP(=S)(OCC)Oc1nc(Cl)c(Cl)cc1Cl.CCOP(=S)(OCC)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
TDP1 Q9NUW8 5/20 1.00
MAPT P10636 4/20 1.00
TSHR P16473 4/20 1.00
CYP3A4 P08684 4/20 1.00
HSD17B10 Q99714 3/20 1.00
MAPK1 P28482 2/20 1.00
ALOX15 P16050 1/20 1.00
ALOX12 P18054 1/20 1.00
ATM Q13315 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
KDM4E B2RXH2 3/20 0.43
TP53 P04637 1/20 0.41
ACHE P22303 1/20 0.41
POLB P06746 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA3 P07451 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorpyrifos SCHEMBL21680 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL14915191 0.98 ALDH1A1 (0.97) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL28566223 0.98 ALDH1A1 (0.97) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL18228939 0.98 ALDH1A1 (0.97) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL28343022 0.98 ALDH1A1 (0.97) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL28945660 0.98 ALDH1A1 (0.97) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL29011072 0.98 ALDH1A1 (0.97) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL29037286 0.97 ALDH1A1 (0.94) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL8502929 0.95 ALDH1A1 (0.91) ALDH1A1TDP1MAPTTSHRCYP3A4
Chlorpyrifos SCHEMBL1069405 0.94 ALDH1A1 (0.89) ALDH1A1TDP1MAPTTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330104-A Pretreatment purifying tube special for quantitative analysis of tobacco pesticide residues and high-throughput detection method of tobacco pesticide residues 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 2024-07-12 CN claimed
CN-116406669-A Weeding combination UPL有限公司 2023-07-11 CN claimed
CN-114965774-B Method for detecting 208 pesticides and metabolite residues in aquatic products 江苏省淡水水产研究所 2024-02-06 CN disclosed
CN-117279508-A Composition for enhancing plant disease control effect and rain resistance of D-tagatose 三井化学植保株式会社 2023-12-22 CN disclosed
CN-116406669-A Weeding combination UPL有限公司 2023-07-11 CN disclosed
WO-2021085278-A1 WEED CONTROL METHOD AND MIXED AGROCHEMICAL COMPOSITION FOR SOIL TREATMENT クミアイ化学工業株式会社 2021-05-06 WO disclosed
WO-2021085277-A1 AGROCHEMICAL COMPOSITION FOR SOIL TREATMENT AND PEST CONTROL METHOD USING SAME クミアイ化学工業株式会社 2021-05-06 WO disclosed
WO-2021002484-A9 HERBICIDE AND PRODUCTION METHOD FOR INTERMEDIATE THEREOF クミアイ化学工業株式会社 2021-04-15 WO disclosed
WO-2021002484-A2 HERBICIDE AND PRODUCTION METHOD FOR INTERMEDIATE THEREOF クミアイ化学工業株式会社 2021-01-07 WO disclosed
WO-2020203963-A1 AGROCHEMICAL COMPOSITION WITH STRENGTHENED EFFICACY 三井化学アグロ株式会社 2020-10-08 WO disclosed
US-6200961-B1 FREE OF VOLATILE ORGANIC COMPOUNDS, STABILITY; FOR CONTROLLING INSECTS AQUATROLS CORPORATION OF AMERICA, INC. 2001-03-13 US disclosed
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
EP-0689377-A4 NOVEL COLLAR TO CONTROL ARTHROPOD INFESTATIONS OF ANIMALS PFIZER (US) 1998-08-12 EP disclosed
EP-0689377-A1 NOVEL COLLAR TO CONTROL ARTHROPOD INFESTATIONS OF ANIMALS PFIZER INC. (US) 1996-01-03 EP disclosed
WO-1994021119-A1 NOVEL COLLAR TO CONTROL ARTHROPOD INFESTATIONS OF ANIMALS PFIZER INC. (US) 1994-09-29 WO disclosed
EP-0312265-B1 ADHESIVE COMPOSITIONS, CONTROLLED RELEASE COMPOSITIONS AND TRANSDERMAL DRUG DELIVERY DEVICE DOW CORNING CORPORATION (US) 1993-03-31 EP disclosed
US-4052381-A SUBSTITUTED PHOSPHOROTHIOIC ACID AND METHOD OF USE IN SIPHONAPTERA COMPOSITIONS IN WARM-BLOODED ANIMALS AMERICAN CYANAMID COMPANY (US) 1977-10-04 US disclosed
US-3978168-A O,O,O',O'-TETRAMETHYL O,O'-TRITHIODI-P-PHENYLENE ESTER AMERICAN CYANAMID COMPANY (US) 1976-08-31 US disclosed
US-3968207-A O,O,O',O'-TETRAMETHYL-O,O'-THIODI-P-PHENYLENE PHOSPHOROTHIOATE AMERICAN CYANAMID COMPANY (US) 1976-07-06 US disclosed
US-3966848-A O,O,O',O'-Tetraethyl-S,S'-methylene-bis(p-phenylenethiomethylene) AMERICAN CYANAMID COMPANY (US) 1976-06-29 US disclosed