SCHEMBL10694078

SCHEMBL10694078

CCCCN(CCCC)S(=O)(=O)c1ccc(Cl)c(N)c1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 6/20 0.65
L3MBTL1 Q9Y468 1/20 0.55
ALDH1A1 P00352 5/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
POLB P06746 2/20 0.53
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.47
TSHR P16473 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11686046 0.85 VCAM1 (0.63) VCAM1L3MBTL1ALDH1A1SMN1; SMN2MAPT
SCHEMBL5461567 0.84 ALDH1A1 (0.65) VCAM1L3MBTL1ALDH1A1SMN1; SMN2POLB
SCHEMBL10859351 0.81 VCAM1 (0.49) VCAM1L3MBTL1ALDH1A1SMN1; SMN2POLB
SCHEMBL5460536 0.81 ESR1 (0.61) VCAM1L3MBTL1ALDH1A1SMN1; SMN2MAPT
SCHEMBL11110731 0.80 L3MBTL1 (0.56) VCAM1L3MBTL1ALDH1A1SMN1; SMN2POLB
SCHEMBL10693029 0.79 SMN1; SMN2 (0.53) VCAM1L3MBTL1SMN1; SMN2POLBMAPT
SCHEMBL10468337 0.79 VCAM1 (1.00) VCAM1L3MBTL1ALDH1A1SMN1; SMN2POLB
SCHEMBL10693896 0.78 CA12 (0.54) VCAM1SMN1; SMN2POLBMAPTLMNA
SCHEMBL8602183 0.78 CA12 (0.59) VCAM1SMN1; SMN2POLBMAPTLMNA
SCHEMBL10687962 0.78 ALDH1A1 (0.47) VCAM1L3MBTL1ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed