Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718307 | 0.80 | ESR2 (0.50) | ESR2DRD2MAP1LC3BMAPTKDM4E | |
| SCHEMBL7243724 | 0.79 | ESR2 (0.48) | ESR2SRD5A1SLC18A3POLBHTT | |
| SCHEMBL444141 | 0.76 | SRD5A1 (0.53) | ESR2SRD5A1HTR3ADRD2ALDH1A1 | |
| SCHEMBL315186 | 0.73 | HTR3A (0.58) | ESR2SRD5A1HTR3ADRD2SLC18A3 | |
| Ethylene SCHEMBL13737971 | 0.72 | ESR2 (0.60) | ESR2SRD5A1HTR3ADRD2SLC18A3 | |
| SCHEMBL3536658 | 0.71 | ESR2 (0.64) | ESR2SRD5A1HTR3ADRD2SLC18A3 | |
| SCHEMBL20011400 | 0.71 | SRD5A1 (0.47) | ESR2SRD5A1HTR3ADRD2SLC18A3 | |
| SCHEMBL11981988 | 0.70 | ESR2 (0.44) | ESR2ALDH1A1NPSR1 | |
| SCHEMBL718300 | 0.69 | ESR2 (0.50) | ESR2SRD5A1HTR3ADRD2SLC18A3 | |
| SCHEMBL435619 | 0.69 | HTR3A (0.59) | ESR2SRD5A1HTR3ADRD2SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544979-B1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-08-04 | — | — | EP | disclosed |
| EP-0253501-A2 | N-disubstituted cycloalkylmethyl amines useful as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |