Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | PLD1 | Q13393 | 7/20 | 0.48 |
| ▸ | PLD2 | O14939 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694355 | 0.92 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL10692072 | 0.88 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL10690442 | 0.86 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL10687790 | 0.83 | PLD1 (0.54) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL31422682 | 0.81 | OPRM1 (0.75) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| Hydrochloric Acid SCHEMBL11033620 | 0.80 | OPRM1 (0.60) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL11031171 | 0.79 | OPRM1 (0.79) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL11031960 | 0.79 | OPRM1 (0.62) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| Hydrochloric Acid SCHEMBL11033857 | 0.78 | OPRM1 (0.62) | OPRM1OPRD1OPRK1OPRL1PLD1 | |
| SCHEMBL10416342 | 0.77 | OPRM1 (0.68) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |