Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697132 | 0.87 | NPC1 (0.48) | CA12CA9NPC1RAB9AHRH3 | |
| SCHEMBL10707505 | 0.84 | CA12 (0.44) | CA12CA9NPC1RAB9AHRH3 | |
| SCHEMBL10698542 | 0.81 | CA12 (0.44) | CA12CA9NPC1RAB9AHRH3 | |
| SCHEMBL10696064 | 0.80 | MEN1 (0.47) | CA12CA9NPC1RAB9ADHFR | |
| SCHEMBL10696205 | 0.76 | CA12 (0.51) | CA12CA9NPC1RAB9AHRH3 | |
| SCHEMBL10695550 | 0.75 | MEN1 (0.47) | CA12CA9NPC1RAB9ADHFR | |
| SCHEMBL10695097 | 0.75 | PARP1 (0.40) | CA12CA9NPC1RAB9AHRH3 | |
| SCHEMBL10698013 | 0.75 | CA12 (0.50) | CA12CA9NPC1RAB9ADHFR | |
| SCHEMBL10696060 | 0.74 | CBFB (0.54) | NPC1RAB9AKMT2AKDM4ELMNA | |
| SCHEMBL10696066 | 0.74 | ALDH1A1 (0.38) | NPC1RAB9AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |