Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10537811 | 0.99 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10541994 | 0.82 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10537421 | 0.78 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| SCHEMBL10362199 | 0.77 | F12 (0.38) | CYP19A1POLBCDK1CCNB1CYP1A2 | |
| SCHEMBL9364502 | 0.76 | CYP11B1 (0.59) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| SCHEMBL10363723 | 0.76 | HDAC6 (0.44) | CYP19A1POLBCDK1CCNB1CYP1A2 | |
| SCHEMBL10694386 | 0.74 | CYP19A1 (0.63) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10537534 | 0.73 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| SCHEMBL6965526 | 0.70 | CYP19A1 (0.70) | CYP19A1CYP11B1CYP11B2POLBCYP17A1 | |
| Hydrochloric Acid SCHEMBL10538936 | 0.70 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2CYP17A1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257171-A1 | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1988-03-02 | — | — | EP | claimed |