Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694565 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL4207495 | 0.81 | HDAC3 (0.48) | SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL30026550 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10940633 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10692302 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL7796358 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL10692445 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL10690890 | 0.77 | HDAC3 (0.49) | SMN1; SMN2ALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL28756536 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10991297 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |