Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694565 | 0.83 | SMN1; SMN2 (0.69) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL10694390 | 0.80 | ALDH1A1 (0.61) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL14818749 | 0.80 | TSHR (0.68) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL11359123 | 0.79 | POLB (0.56) | ALDH1A1RAB9ALMNAPOLBMAPT | |
| SCHEMBL10693261 | 0.79 | NPC1 (0.66) | ALDH1A1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10996044 | 0.78 | ALDH1A1 (0.63) | TDP1ALDH1A1NPY1RNPY2RLMNA | |
| SCHEMBL9312836 | 0.77 | HDAC3 (0.67) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL528445 | 0.76 | KCNK3 (0.77) | ALDH1A1RAB9ALMNAPOLBMAPT | |
| SCHEMBL3022920 | 0.76 | HDAC3 (0.65) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL10693611 | 0.75 | HDAC3 (0.57) | TDP1ALDH1A1RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |