Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796358 | 0.91 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10689596 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10691781 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10693527 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL9167530 | 0.82 | L3MBTL1 (0.56) | SMN1; SMN2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL10694565 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10694549 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL4237601 | 0.80 | L3MBTL1 (0.62) | SMN1; SMN2ALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL28756536 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10692445 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |