Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 7/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730635 | 0.80 | SELL (0.38) | SELLSELPSELEAPPEP300 | |
| SCHEMBL21729845 | 0.73 | APP (0.45) | APPEP300KAT2BKAT8ESR1 | |
| SCHEMBL8762568 | 0.71 | EP300 (0.47) | APPEP300KAT2BKAT8ESR1 | |
| SCHEMBL2220478 | 0.71 | SELL (0.50) | SELLSELPSELEACHECYP2C9 | |
| SCHEMBL4028857 | 0.70 | ACHE (0.39) | APPACHEEP300KAT2BKAT8 | |
| SCHEMBL440101 | 0.70 | MCL1 (0.33) | APPMCL1ALDH1A1 | |
| SCHEMBL145247 | 0.69 | SELL (0.48) | SELLSELPSELEAPPACHE | |
| Methane SCHEMBL2219191 | 0.69 | SELL (0.48) | SELLSELPSELEACHECYP2C9 | |
| SCHEMBL28242686 | 0.69 | APP (0.47) | APPEP300KAT2BKAT8ESR1 | |
| SCHEMBL15398482 | 0.68 | CA1 (0.37) | ACHEESR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254097-A2 | Catalyst mixtures for polyisocyanurate foam | THE CELOTEX CORPORATION (US) | 1988-01-27 | — | — | EP | disclosed |