SCHEMBL440101

SCHEMBL440101

Cc1c(N(C)C)cc(N(C)C)c(O)c1N(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.33
APP P05067 2/20 0.32
MAOA P21397 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11210094 0.90 MAOA (0.31) MAOAALDH1A1TSHR
SCHEMBL15398482 0.84 CA1 (0.37) MAOAALDH1A1
SCHEMBL8061109 0.72 GABRA1 (0.31) MCL1APP
SCHEMBL9577023 0.71 CYP3A4 (0.38) MCL1ALDH1A1TSHR
SCHEMBL8349290 0.70 SELL (0.46) MCL1APPMAOAALDH1A1TSHR
SCHEMBL10694592 0.70 SELL (0.40) MCL1APPALDH1A1
SCHEMBL12818447 0.68
SCHEMBL11406430 0.68 EP300 (0.36) APPALDH1A1TSHR
SCHEMBL4028857 0.68 ACHE (0.39) APP
SCHEMBL8705091 0.67 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015521-A1 THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE EASTMAN CHEMICAL COMPANY (US) 2026-01-15 US claimed
US-12421417-B2 Thermosetting coating composition with improved scratch resistance EASTMAN CHEMICAL COMPANY (US) 2025-09-23 US claimed
CN-116622053-A Self-extinction photo-curing resin, UV matte coating and wearable first sheet prepared from self-extinction photo-curing resin 河源华造新材料有限公司 2023-08-22 CN claimed
US-20220002579-A1 THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE EASTMAN CHEMICAL COMPANY (US) 2022-01-06 US claimed
US-20210348016-A1 THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE EASTMAN CHEMICAL COMPANY (US) 2021-11-11 US claimed
EP-3864100-A1 THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE Eastman Chemical Company (US) 2021-08-18 EP claimed
EP-3433324-B1 CURABLE POLYESTER POLYOLS AND THEIR USE IN THERMOSETTING SOFT FEEL COATING FORMULATIONS EASTMAN CHEM CO (US) 2020-09-02 EP claimed
EP-2588508-B2 SILYL-TERMINATED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-04-29 EP claimed
EP-3433324-A1 CURABLE POLYESTER POLYOLS AND THEIR USE IN THERMOSETTING SOFT FEEL COATING FORMULATIONS Eastman Chemical Company (US) 2019-01-30 EP claimed
US-10011737-B2 Curable polyester polyols and their use in thermosetting soft feel coating formulations EASTMAN CHEMICAL COMPANY (US) 2018-07-03 US claimed
WO-2003031507-A2 POLYESTER AND POLYAMIDE COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-04-17 WO claimed
EP-0556414-B1 Permanently elastic multipurpose mass and process for its production GERHARD KERTSCHER CHEMISCHE BA (DE) 1994-05-18 EP claimed
EP-0556414-A1 Permanently elastic multipurpose mass and process for its production GERHARD KERTSCHER CHEMISCHE BAUSTOFFE GmbH & Cie. (DE) 1993-08-25 EP claimed
US-4954602-A FIXING WINDINGS OF A COIL; CONTAINING BISPHENOL A EPOXY RESIN, ALICYCLIC EPOXY AND A CURING AGENT CONTAINING AN ACID ANHYDRIDE AND A PHENOL COMPOUND SOMAR CORPORATION (JP) 1990-09-04 US claimed
US-4902736-A COMPONENT WITH SILYLTHIO ETHER GROUPS AND POLYESTHERURETHANE OR POLYETHERURETHANE COPOLYMER;FREE OF CARBON DIOXIDE; HEAT RESISTANCE TORAY THIOKOL COMPANY LIMITED (JP) 1990-02-20 US claimed
EP-0349192-A2 Liquid, epoxy resin composition SOMAR CORPORATION (JP) 1990-01-03 EP claimed
EP-0034309-B1 USE OF EPOXY CASTING RESIN MASSES FOR PREPARING PRINTING MECHANISMS OF THE WRITING JET TYPE WITH MULTIPLE NOZZLES SIEMENS AKTIENGESELLSCHAFT (DE) 1984-04-11 EP claimed
US-4294733-A HOT MELT ADHESIVE, BLOCK COPOLYMER AND POLYEPOXIDE USM CORPORATION (US) 1981-10-13 US claimed
EP-0034309-A2 Use of epoxy casting resin masses for preparing printing mechanisms of the writing jet type with multiple nozzles SIEMENS AKTIENGESELLSCHAFT (DE) 1981-08-26 EP claimed
US-4013625-A Process for the linearization of polyurethanes with lactams and lactam addition compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015521-A1 THERMOSETTING COATING COMPOSITION WITH IMPROVED SCRATCH RESISTANCE PCNA, SDC2, ERCC1 MCL1 3862/4885APP 2840/4885MAOA 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.